This message means that the the time stamp (modification date/time) of the file in the database is different from the file that is stored in /etc/asterisk folder.

This usually means that somebody has modified the file manually (either by actually modifying it or copying it from other place) and not through the web interface.

RESOLUTION:

• Click on 'Save' to save the current file from the database to the server or
• Click on 'Import current file' to import the current file from the server into the database
• Click on the 'Reload' button to reload the system configuration files